Evolving Linear Chromosomes and Telomeres: A C-Strand-Centric View
نویسندگان
چکیده
منابع مشابه
C. elegans Telomeres Contain G-Strand and C-Strand Overhangs that Are Bound by Distinct Proteins
Single-strand extensions of the G strand of telomeres are known to be critical for chromosome-end protection and length regulation. Here, we report that in C. elegans, chromosome termini possess 3' G-strand overhangs as well as 5' C-strand overhangs. C tails are as abundant as G tails and are generated by a well-regulated process. These two classes of overhangs are bound by two single-stranded ...
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ژورنال
عنوان ژورنال: Trends in Biochemical Sciences
سال: 2018
ISSN: 0968-0004
DOI: 10.1016/j.tibs.2018.02.008